Databases Construction of the Marine Metagenomics

The study of marine microbial communities will help us understand the repertoire of microorganisms adapted to specific niches, and ultimately the microbial dynamics underlying their interactions in the biosphere. Dynamic changes in marine microbial diversity can be used to monitor environmental conditions to predict catastrophic and harmful changes in the environment. It also facilitates efficient exploration of novel and useful proteins and metabolites for industrial applications. In fact, the vast library of microorganisms can be regarded as a valuable resource for potential drugs and materials. Metagenomes are an effective method to examine the diversity of microbial communities. Due to its wide range of applications, metagenomics has become a very popular method, especially when it is used in conjunction with next-generation sequencing (NGS) technologies. In these cases, metagenomic studies generate large amounts of data. Undoubtedly, without proper management of such a large amount of data, any metagenomic study will not obtain any important results. It can be seen that the construction of the database is an important key to ensure the success of metagenomic research.

Fig. 1 Common analysis procedures for metagenomics data. (Breitwieser F P, et al., 2019)

Our Services

Marine microorganisms have attracted the attention of natural product chemists as well as synthetic chemists, biochemists and pharmacologists because of their diverse and very robust biological roles. With years of research experience in marine microbes, CD BioSciences can provide our customers with one-stop services, whether it is metagenomic data collection or metagenomic database construction. Our services are listed below, but not limited to:

• Data generation in marine metagenomics
• Databases classification for marine metagenomics
• Database design of marine metagenomics
• Databases construction of the marine metagenomics
• Metagenomic assembly

Data Generation for Two Approaches in Marine Metagenomics

The rapid growth of marine metagenomic data is mainly due to the advances in sequencing capabilities of NGS technologies in recent years. NGS-based metagenomic studies use two different approaches:

• Amplicon-based Approach
  Amplicon-based approaches using rRNA genes as targets are the most widely used methods in marine metagenomic research. CD BioSciences uses this method to generate large numbers of 16S rRNA gene fragments from diverse marine microbial communities in a cost-effective and rapid manner. Likewise, the 18S rRNA gene was used to identify marine eukaryotic microorganisms.
• Shotgun Sequencing-based Approach
  Shotgun based methods are more time consuming and costly. CD BioSciences uses this method to generate large numbers of short sequences (200-1000 bp) from different regions of the genome, not just rRNA genes.

CD BioSciences is a professional service provider for the marine biology industry. Our marine microbial viability test services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Reference

• Breitwieser F P, Lu J, Salzberg S L. A review of methods and databases for metagenomic classification and assembly[J]. Briefings in bioinformatics, 2019, 20(4): 1125-1136.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).