Development of Marine Antibacterial Drug

Marine organisms comprising microbes, plants, invertebrates, and vertebrates have crafted an impressive array of structurally diverse antimicrobial products ranging from small cyclic compounds to macromolecules such as proteins. Some biomolecules originated directly from marine animals, while others originated from animal-associated microbes. It is worth noting that some of the biomolecules mentioned above are structurally unique, while others belong to known classes of compounds, peptides, and proteins. Some antimicrobials are effective against Gram-positive bacteria, while others are effective against Gram-negative bacteria. Some are effective against both gram-positive and gram-negative bacteria and resistant strains. Marine organisms are a promising source of novel bioactive substances for therapeutic development.

CD BioSciences is committed to helping our clients solve their most essential and complex marine antimicrobial drug discovery and development challenges. Our scientific knowledge base, technical expertise, and reputation for high-quality service are integral to our ability to turn services into solutions.

Our Services

Because marine environments are more diverse and saltier than terrestrial environments, we took a different approach than terrestrial microbes to optimize culture media to increase the production of target biomolecules.

• Marine Antibacterial Discovery
  CD BioSciences offers a range of early discovery services to assist sponsors in target discovery and validation to optimize their lead compound development.
• Antibacterial Candidate Evaluation
  At CD BioSciences, we offer a comprehensive portfolio of antibacterial candidate evaluation services, including DMPK, safety and toxicology, and bioanalytical related services.
• Marine Antimicrobial Development
  Our product development portfolio spans from drug discovery to preclinical stages, including lead quantification and analytical testing.
• Chemical Modification of Marine Antimicrobial
  Post-translational modifications of marine antimicrobials include: disulfide bonds, bromination, chlorination, C-terminal amidation, high levels of specific amino acids (e.g., phenylalanine, arginine), modification of single amino acids (e.g., 3-methylisoleucine), presence of fatty acids linked to peptide sequences, and presence of d-amino acids.

Main Sources of Our Marine Antibacterials

Our antibacterial compounds are mainly isolated from the following marine organisms, and we analyze the type, source and antibacterial activity of each group of antibacterial compounds. We also analyzed the immune mechanism from three aspects: membrane-targeted direct killing effect, non-membrane-targeted effect and immunomodulatory effect.

• Bacteria
• Fungi
• Algae
• Sponges
• Cnidarians
• Arthropods
• Echinoderms
• Mollusks
• Fish
• Reptiles

Why should a client choose our company?

• Scientific team with extensive experience in handling marine organism
• Fully customizable designs to meet each specific need
• Through the use of advanced equipment such as submarines or remote-controlled vehicles, we can explore otherwise inaccessible environments for biological sample collection.
• Advanced platform to ensure optimal results for every step
• Fast turnaround time and reasonable price
• Reliable and up-to-date analysis reports
• Friendly, expert advice available

CD BioSciences is a professional service provider for the marine biology industry. Our marine antibacterials development services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).