Development of Marine-Based Biomaterials for Tissue Engineering

Tissue engineering is a promising approach to use scaffolding materials to replace or improve tissue lost or rendered non-viable due to disease or trauma by combining engineering and biochemical/physicochemical approaches. Its purpose is to create a suitable matrix that supports cell differentiation and proliferation to form new functional tissues. Using materials that mimic the biochemical and mechanical properties of natural tissue minimizes irritation to the organism and enables longer durability: ideally, biomimetic biomaterials that can be fully integrated into the body could be used in the future. Marine-based natural compounds are potential scaffold raw materials in tissue engineering because of their biocompatibility and biodegradability combined with excellent biochemical/physicochemical properties. Other marine structures such as corals and shells also have the potential to be used as biomimetic scaffolds for bone tissue engineering and regenerative medicine. Marine-derived scaffolds for bone tissue regeneration are considered superior because they are more biocompatible and provide more biological interaction sites for cell attachment, and have a structure that mimics the trabecular network of bone tissue.

Our Services

We have expertise in marine-based materials science, including the design, fabrication and analysis of biomaterials using natural and synthetic polymers.

• Development of Marine-Based Biomaterials for Hard Tissue
  Collagen, which is abundantly present in marine species, offers an interesting alternative source for pharmaceutical and biomedical applications. Our scientists developed collagen membrane from marine-derived collagen from different echinoderms (sea urchins, starfish and sea cucumbers).
• Development of Marine-Based Biomaterials for Skin Tissue
  Our scientists use marine biological sources to extract collagen, and the collagen scaffold produced has the characteristics of high-water absorption, elasticity, high temperature resistance and bacterial invasion, and has high potential for clinical application.
• Development of Marine-Based Biomaterials for Cardiovascular Tissue
  Our scientists extract marine lipids from marine organisms such as invertebrates, especially eicosapentaenoic acid EPA and docosahexaenoic acid DHA for the development of Cardiovascular tissue materials.
• Development of Marine-Based Biomaterials for Liver Tissue
  Tissue-engineered scaffolds derived from marine organisms can preserve an appropriate microenvironment for human embryonic stem cells to regenerate fully functional hepatocytes.

Our Capabilities

• By controlling material composition, structure, and morphology, we can create dynamically bioactive materials that mimic those found in vivo and/or can stimulate tissue repair. These materials can be used in the development of in vitro models.
• We are very active in the development of bioactive materials for a variety of tissue types, including musculoskeletal and nerve regeneration and mucosal tissue engineering.

CD BioSciences is a professional service provider for the marine biology industry. Our development services of marine-based material can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).