Development of Marine Anticoagulant Drug

Thrombosis remains the leading cause of death worldwide. With existing antithrombotic agents, bleeding remains a major drawback of current treatments. This raises clinical concerns in all patients receiving antithrombotic therapy. Novel antithrombotic agents from the ocean offer a promising therapeutic alternative for this pathology. However, for any potential new molecule to serve as a true replacement for existing drugs, it must demonstrate comparable anticoagulant potential with minimal off-target effects. The marine environment harbors diverse species consisting of a wide variety of therapeutic molecules. Marine organisms are affected by different environmental conditions compared to terrestrial organisms, and marine organisms produce chemically and structurally unique molecules/metabolites as an adaptive strategy to survive in water bodies. The relevance of marine antithrombotic agents, especially sulfated polysaccharides, is largely due to their unique mechanism of action and absence of bleeding. In recent years, many investigations have been carried out in this field, and the results have confirmed the role of potential marine molecules as alternative antithrombotic drugs.

Our Services

Our investment in state-of-the-art facilities and highly trained specialists underscores our commitment to delivering a positive client experience at all stages of drug development. Throughout the lifecycle of your drug development project, you'll have a consistent team and easy, regular access to the functions you need to move your project forward.

• Marine Organism Collection and Screening
  We have established a large collection of marine organisms, including sponges, algae, and fungi, sourced from diverse marine environments worldwide.
• Marine-derived Compound Isolation and Characterization
  We employ chromatographic techniques, spectroscopy, and mass spectrometry to identify and characterize anticoagulant compounds, determining their chemical structures and physicochemical properties.
• In Vitro Anticoagulant Activity Testing
  We evaluate parameters such as clotting time, inhibition of coagulation factors, platelet aggregation, and anti-thrombin activity to determine the potency and mechanism of action of the marine-derived compounds.
• Assay Development and Screening
  Our scientists evaluate new antithrombotic drug candidates at the cellular, molecular, and biochemical levels.

Accelerate Drug Development

Bringing a new drug to market is a complex process that includes discovery (target identification and validation, hit identification, lead generation, and optimization, identification of viable drug candidates for future and further development) and development (optimization of chemical synthesis and formulation, toxicology research). CD BioSciences expertise spans the following discovery and development capabilities:

• Technical transformation
• Research platform
• Target recognition
• Lead verification

CD BioSciences is a professional service provider for the marine biology industry. Our marine anticoagulant drug development services can ensure that the most suitable methods and techniques are selected for your project. We provide our customers with the most precise ingredient data and highly informed process expertise. Our team of biomass experts plays a key role in the formulation, optimization and commercial evaluation of biomass value-added processes in industry and academia. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).